Identification of immuno-reactive proteins from a sheep gastrointestinal nematode, Trichostrongylus colubriformis, using two-dimensional electrophoresis and mass …

M Kiel, P Josh, A Jones, R Windon, P Hunt… - International journal for …, 2007 - Elsevier
Gastrointestinal nematode infections of livestock animals are prevalent and costly problems
worldwide. Currently, infections are controlled by anthelmintic chemicals but increasing drug
resistance has prompted research interest to shift towards alternative methods of control
such as vaccine development and selection of worm-resistant animals. The present study
analyses proteins from Trichostrongylus colubriformis infective L3s that are recognised by
IgG of immune sheep. Following protein separation via two-dimensional electrophoresis and …
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